| Abstract |
Purpose: This study was designed to determine the comprehensive effects of a respiratory rehabilitation program on the
immune system, pulmonary function, motor ability, and activities of daily living (ADLs) in a patient with severe coronavirus
disease 2019 (COVID-19). Methods: A 73-year-old female patient diagnosed with severe COVID-19 was recruited at OO
university hospital. The respiratory rehabilitation program was conducted for 8 weeks, 5 days per week, for 120 min per
day, and consisted of aerobic and strength exercises. We assessed the changes in the immune system-related cells and
inflammatory markers, dyspnea, coughing ability, respiratory muscle strength, pulmonary functions, upper and lower
extremity strength, balance, walking speed, and ADLs. Results: The lymphocytes showed a meaningful increase after the
intervention, whereas the level of C-reactive protein and erythrocyte sedimentation rate decreased, suggesting the setting
down of inflammation. COVID-19-related dyspnea was reduced, and the coughing ability of the patient was improved.
Finally, there were remarkable increases in the upper and lower extremity strength, balance, walking speed, and ADL
assessments. Conclusion: Hence, we suggest that the respiratory rehabilitation program, which includes aerobic and
strength exercises, helps patients with COVID-19 relieve the main symptoms, such as dyspnea and cough, and improve
the immune system and pulmonary function, motor ability, and ADLs. |