학술지
| 발행연도 | 2026/07/31 | ||
|---|---|---|---|
| 권 | 14 | 호 | 2 |
| 페이지 | 47-58(12) | ||
| 제목 | 심혈관질환 환자에서 근감소증 관련 표현형에 따른 심폐운동능력 및 신체수행능력의 특성: 사례연구 | ||
| 저자 | ■김세윤1, 강병창1, 박민영2, 우현재3* | ||
| 교신저자 | 우현재 | ||
| 소속 | ■1부천세종병원 심장재활센터, 2독립 연구자, *3와카야마리하빌리테이션전문직대학 물리치료학과 | ||
| Abstract | This study investigated the prevalence of sarcopenia-related phenotypes in patients with cardiovascular diseases and examined the associations between these phenotypes and cardiorespiratory fitness and physical performance. Methods: This retrospective observational study examined electronic medical records of patients who underwent cardiopulmonary exercise testing(CPET), body composition assessment, handgrip strength, Short Physical Performance Battery(SPPB), 6-m gait speed, and echocardiography on the same day at a cardiac rehabilitation center of a tertiary hospital. Sarcopenia, functional sarcopenia, and sarcopenic obesity were identified using the AWGS 2019, KWGS 2023, and JWGSO 2024 definitions, respectively. We used group comparisons and minimally adjusted multiple linear regression analyses to assess functional differences and independent associations between sarcopenia status and major physical performance outcomes. Results: Among 61 patients with cardiovascular disease, 19.7% had sarcopenia-related phenotypes(sarcopenia 3.3%, functional sarcopenia 9.8%, sarcopenic obesity 6.6%). Compared with the non-sarcopenia group, those with sarcopenia-related phenotypes showed significantly lower VO2peak, peak METs, handgrip strength, tidal volume at peak exercise, and 6-m gait speed, with large effect sizes(Cohen’s d≥0.80). Multiple regression analysis revealed that sarcopenia status was independently associated with slower 6-m gait speed(β=-0.18 m/s, p=.021), whereas VO2peak and SPPB scores were more strongly influenced by age, sex, and BMI than by sarcopenia itself. Left ventricular ejection fraction had no significant association with functional outcomes. Conclusion: Sarcopenia-related phenotypes are relatively common in patients with cardiovascular disease and are associated with clinically meaningful impairments in exercise capacity and physical performance, particularly gait speed and respiratory muscle-related ventilatory response. These findings highlight the significance of phenotype-based assessment in cardiac rehabilitation and support the need for individualized rehabilitation strategies incorporating muscle strength, gait function, body composition, and respiratory muscle performance. | ||
| 키워드 | Cardiopulmonary exercise test, Functional sarcopenia, Gait speed, Sarcopenic obesity, Sarcopenia | ||
| 첨부파일 #1 | 06_김세윤,_강병창,_박민영,_우현재(47-58).pdf | ||