Abstract |
This study primarily aimed to examine the association between walking time during hospitalization and the
health-related quality of life (HRQOL) at discharge among older patients with community-acquired pneumonia (CAP). The
secondary aim was to investigate the relationship between the HRQOL and sum of all sedentary (sitting/lying) bouts ≥
60 min. Methods: This retrospective observational study analyzed the physical activity data from 81 patients aged ≥65
years who were hospitalized for CAP between April 2017 and February 2019. Walking time, measured using a
thigh-mounted accelerometer, was analyzed as the primary independent variable. HRQOL was assessed using the EuroQol
5 Dimensions 3 Level (EQ-5D-3L) utility index at discharge. Multivariable linear regression was conducted, adjusting for
age, sex, comorbidity index, pneumonia severity, nutritional status, cognitive function, and activities of daily living.
Results: The median daily walking time was 12 (IQ R: 5–25) min, and the median EQ-5D utility score at discharge was
0.768 (IQR: 0.640–1.000). The walking time showed a significant positive association with EQ-5D utility (β=.005, p=.040),
with an adjusted R² of 0.209 (p=.002). In a secondary analysis, the sum of all sedentary bouts ≥ 60 min was significantly
negatively associated with EQ-5D utility. Conclusion: In-hospital walking time and prolonged sedentary behavior were
significantly associated with the HRQOL at discharge. These findings indicate the potential critical role of early
mobilization with limited continuous bed rest in maintaining the quality of life in older patients hospitalized for CAP. |